Assay Detail
Binding
CHEMBL4035202
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Inhibition of HDAC2 (unknown origin)
5
Total Activities
5
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis and applications of benzohydroxamic acid-based histone deacetylase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.66 | 4.69 |
| Ki | 1 | 7.70 | 7.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2103863 | ABEXINOSTAT | 3.0 | 1 | 7.70 |
| CHEMBL4080014 | — | — | 1 | 4.69 |
| CHEMBL4104247 | — | — | 1 | 4.62 |
| CHEMBL2018302 | TUBASTATIN A | — | 1 | - |
| CHEMBL4069287 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2103863 | ABEXINOSTAT | Ki | = | 20.0 | nM | 7.70 |
| CHEMBL4080014 | — | IC50 | = | 20300.0 | nM | 4.69 |
| CHEMBL4104247 | — | IC50 | = | 24000.0 | nM | 4.62 |
| CHEMBL2018302 | TUBASTATIN A | IC50 | > | 30000.0 | nM | - |
| CHEMBL4069287 | — | IC50 | > | 30000.0 | nM | - |