Assay Detail
Binding
CHEMBL4035522
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Inhibition of CK2alpha (unknown origin) using RRRADDSDDDD as substrate after 40 mins by ADP-Glo assay
2
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
A fragment-based approach leading to the discovery of a novel binding site and the selective CK2 inhibitor CAM4066.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| INH | 1 | - | - |
| IC50 | 1 | 6.43 | 6.43 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4070389 | — | — | 1 | 6.43 |
| CHEMBL1161012 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4070389 | — | IC50 | = | 370.0 | nM | 6.43 |
| CHEMBL1161012 | — | INH | = | 100.0 | uM | - |