Assay Detail
Functional
CHEMBL4035949
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Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 24 hrs by MTS assay
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MCF7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Screening for bioactive natural products from a 67-compound library of Glycyrrhiza inflata.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 9 | 5.03 | 5.14 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4088099 | — | — | 1 | 5.14 |
| CHEMBL3810262 | — | — | 1 | 5.13 |
| CHEMBL462721 | GLABROL | — | 1 | 5.12 |
| CHEMBL4064421 | — | — | 1 | 5.07 |
| CHEMBL494252 | — | — | 1 | 5.07 |
| CHEMBL1644933 | KANZONOL C | — | 1 | 5.04 |
| CHEMBL4083261 | — | — | 1 | 4.91 |
| CHEMBL2437376 | — | — | 1 | 4.89 |
| CHEMBL256340 | LESPEDEZAFLAVANONE B | — | 1 | 4.88 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4088099 | — | IC50 | = | 7270.0 | nM | 5.14 |
| CHEMBL3810262 | — | IC50 | = | 7470.0 | nM | 5.13 |
| CHEMBL462721 | GLABROL | IC50 | = | 7620.0 | nM | 5.12 |
| CHEMBL4064421 | — | IC50 | = | 8580.0 | nM | 5.07 |
| CHEMBL494252 | — | IC50 | = | 8580.0 | nM | 5.07 |
| CHEMBL1644933 | KANZONOL C | IC50 | = | 9150.0 | nM | 5.04 |
| CHEMBL4083261 | — | IC50 | = | 12220.0 | nM | 4.91 |
| CHEMBL2437376 | — | IC50 | = | 12930.0 | nM | 4.89 |
| CHEMBL256340 | LESPEDEZAFLAVANONE B | IC50 | = | 13130.0 | nM | 4.88 |