Assay Detail
Functional
CHEMBL4035950
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Cytotoxicity against human SW480 cells assessed as reduction in cell viability after 24 hrs by MTS assay
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SW480 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Screening for bioactive natural products from a 67-compound library of Glycyrrhiza inflata.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 5.13 | 5.33 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3810262 | — | — | 1 | 5.33 |
| CHEMBL462721 | GLABROL | — | 1 | 5.29 |
| CHEMBL1644933 | KANZONOL C | — | 1 | 5.21 |
| CHEMBL4061417 | — | — | 1 | 5.20 |
| CHEMBL4064421 | — | — | 1 | 5.17 |
| CHEMBL4088099 | — | — | 1 | 5.10 |
| CHEMBL494252 | — | — | 1 | 5.09 |
| CHEMBL2437376 | — | — | 1 | 5.01 |
| CHEMBL3125437 | — | — | 1 | 4.98 |
| CHEMBL256340 | LESPEDEZAFLAVANONE B | — | 1 | 4.90 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3810262 | — | IC50 | = | 4620.0 | nM | 5.33 |
| CHEMBL462721 | GLABROL | IC50 | = | 5150.0 | nM | 5.29 |
| CHEMBL1644933 | KANZONOL C | IC50 | = | 6100.0 | nM | 5.21 |
| CHEMBL4061417 | — | IC50 | = | 6350.0 | nM | 5.20 |
| CHEMBL4064421 | — | IC50 | = | 6720.0 | nM | 5.17 |
| CHEMBL4088099 | — | IC50 | = | 7870.0 | nM | 5.10 |
| CHEMBL494252 | — | IC50 | = | 8080.0 | nM | 5.09 |
| CHEMBL2437376 | — | IC50 | = | 9840.0 | nM | 5.01 |
| CHEMBL3125437 | — | IC50 | = | 10500.0 | nM | 4.98 |
| CHEMBL256340 | LESPEDEZAFLAVANONE B | IC50 | = | 12530.0 | nM | 4.90 |