Assay Detail
Functional
CHEMBL4035951
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Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 24 hrs by MTS assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HepG2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Screening for bioactive natural products from a 67-compound library of Glycyrrhiza inflata.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.33 | 5.55 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL462721 | GLABROL | — | 1 | 5.55 |
| CHEMBL4088099 | — | — | 1 | 5.45 |
| CHEMBL3810262 | — | — | 1 | 5.25 |
| CHEMBL3125437 | — | — | 1 | 5.25 |
| CHEMBL4064421 | — | — | 1 | 5.15 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL462721 | GLABROL | IC50 | = | 2830.0 | nM | 5.55 |
| CHEMBL4088099 | — | IC50 | = | 3540.0 | nM | 5.45 |
| CHEMBL3810262 | — | IC50 | = | 5660.0 | nM | 5.25 |
| CHEMBL3125437 | — | IC50 | = | 5650.0 | nM | 5.25 |
| CHEMBL4064421 | — | IC50 | = | 7070.0 | nM | 5.15 |