Assay Detail
Binding
CHEMBL4035960
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Inhibition of LPS-induced NF-kappaB transcription (unknown origin) expressed in human SW480 cells by luciferase reporter gene assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Screening for bioactive natural products from a 67-compound library of Glycyrrhiza inflata.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.29 | 5.61 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2437370 | — | — | 1 | 5.61 |
| CHEMBL233766 | — | — | 1 | 5.51 |
| CHEMBL1779057 | LICOCHALCONE E | — | 1 | 5.42 |
| CHEMBL4076010 | — | — | 1 | 5.18 |
| CHEMBL561840 | — | — | 1 | 5.14 |
| CHEMBL139702 | LICOAGROCHACONE A | — | 1 | 4.86 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2437370 | — | IC50 | = | 2440.0 | nM | 5.61 |
| CHEMBL233766 | — | IC50 | = | 3100.0 | nM | 5.51 |
| CHEMBL1779057 | LICOCHALCONE E | IC50 | = | 3830.0 | nM | 5.42 |
| CHEMBL4076010 | — | IC50 | = | 6670.0 | nM | 5.18 |
| CHEMBL561840 | — | IC50 | = | 7270.0 | nM | 5.14 |
| CHEMBL139702 | LICOAGROCHACONE A | IC50 | = | 13900.0 | nM | 4.86 |