Assay Detail
Functional
CHEMBL4038376
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Antiprotozoal activity against amastigote form of Leishmania donovani MHOM/ET/67/L82 after 72 hrs by Alamar Blue assay
13
Total Activities
13
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Leishmania donovani |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Antiprotozoal Activity-Based Profiling of a Dichloromethane Extract from Anthemis nobilis Flowers.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 13 | 5.77 | 6.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL125 | MILTEFOSINE | 4.0 | 1 | 6.89 |
| CHEMBL4059870 | — | — | 1 | 6.42 |
| CHEMBL4070082 | — | — | 1 | 6.30 |
| CHEMBL4101872 | — | — | 1 | 6.30 |
| CHEMBL4094141 | — | — | 1 | 6.10 |
| CHEMBL4075374 | — | — | 1 | 5.80 |
| CHEMBL4103119 | — | — | 1 | 5.57 |
| CHEMBL4076872 | — | — | 1 | 5.57 |
| CHEMBL4076244 | — | — | 1 | 5.28 |
| CHEMBL4070737 | — | — | 1 | 5.08 |
| CHEMBL4076328 | — | — | 1 | 5.01 |
| CHEMBL4068842 | — | — | 1 | 4.88 |
| CHEMBL4080773 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL125 | MILTEFOSINE | IC50 | = | 130.0 | nM | 6.89 |
| CHEMBL4059870 | — | IC50 | = | 380.0 | nM | 6.42 |
| CHEMBL4070082 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL4101872 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL4094141 | — | IC50 | = | 800.0 | nM | 6.10 |
| CHEMBL4075374 | — | IC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL4103119 | — | IC50 | = | 2700.0 | nM | 5.57 |
| CHEMBL4076872 | — | IC50 | = | 2700.0 | nM | 5.57 |
| CHEMBL4076244 | — | IC50 | = | 5300.0 | nM | 5.28 |
| CHEMBL4070737 | — | IC50 | = | 8400.0 | nM | 5.08 |
| CHEMBL4076328 | — | IC50 | = | 9800.0 | nM | 5.01 |
| CHEMBL4068842 | — | IC50 | = | 13200.0 | nM | 4.88 |
| CHEMBL4080773 | — | IC50 | = | 230000.0 | nM | - |