Assay Detail
Functional
CHEMBL4039146
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Antileishmanial activity against Leishmania donovani LV9 amastigotes infected in mouse peritoneal macrophages after 72 hrs
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Leishmania donovani |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Nitroimidazoles: Molecular Fireworks That Combat a Broad Spectrum of Infectious Diseases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 5.94 | 7.06 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL218650 | DELAMANID | 4.0 | 1 | 7.06 |
| CHEMBL125 | MILTEFOSINE | 4.0 | 1 | 5.48 |
| CHEMBL1631696 | FEXINIDAZOLE SULFONE | — | 1 | 5.28 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL218650 | DELAMANID | EC50 | = | 87.0 | nM | 7.06 |
| CHEMBL125 | MILTEFOSINE | EC50 | = | 3300.0 | nM | 5.48 |
| CHEMBL1631696 | FEXINIDAZOLE SULFONE | EC50 | = | 5300.0 | nM | 5.28 |