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Assay Detail

CHEMBL4039148

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antileishmanial activity against Leishmania donovani LV9 amastigotes infected in BALB/c mouse peritoneal macrophages after 72 hrs by resazurin-based fluorescence assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Leishmania donovani
Confidence 1 — Organism
Curated By Autocuration

Target

Leishmania donovani (CHEMBL367)
Type ORGANISM
Organism Leishmania donovani

Publication

Nitroimidazoles: Molecular Fireworks That Combat a Broad Spectrum of Infectious Diseases.
Ang CW, Jarrad AM, Cooper MA, Blaskovich MAT.
J Med Chem (2017) 60 : 7636 -7657
PubMed 28463485 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 6.03 6.03

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL512244 1 6.03

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL512244 EC50 = 930.0 nM 6.03