Assay Detail
Binding
CHEMBL4040845
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Noncompetitive inhibition of human recombinant microsomal MAOB expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate assessed as decrease in H2O2 production by Lineweaver-Burk plot analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Coumarin versus Chromone Monoamine Oxidase B Inhibitors: Quo Vadis?
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 8.75 | 8.93 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL494798 | — | — | 1 | 8.93 |
| CHEMBL4060916 | — | — | 1 | 8.57 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL494798 | — | Ki | = | 1.17 | nM | 8.93 |
| CHEMBL4060916 | — | Ki | = | 2.69 | nM | 8.57 |