Assay Detail
Functional
CHEMBL4041259
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Antiproliferative activity against human MGC803 cells after 48 hrs by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MGC-803 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Design, Synthesis, and Biological Evaluation of Novel Selenium-Containing Isocombretastatins and Phenstatins as Antitumor Agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.93 | 8.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4089545 | — | — | 1 | 8.05 |
| CHEMBL67 | COMBRETASTATIN A4 | -1.0 | 1 | 8.05 |
| CHEMBL498271 | — | — | 1 | 7.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4089545 | — | IC50 | = | 9.0 | nM | 8.05 |
| CHEMBL67 | COMBRETASTATIN A4 | IC50 | = | 8.9 | nM | 8.05 |
| CHEMBL498271 | — | IC50 | = | 19.8 | nM | 7.70 |