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Assay Detail

CHEMBL4041840

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of recombinant rabbit N-terminal His-tagged GSK3beta expressed in Escherichia coli using GS-1 as substrate after 20 mins in presence of [gamma32P]ATP by liquid scintillation counting method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Oryctolagus cuniculus
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Natural and synthetic bioactive inhibitors of glycogen synthase kinase.
Khan I, Tantray MA, Alam MS, Hamid H.
Eur J Med Chem (2017) 125 : 464 -477
PubMed 27689729 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.70 5.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL284861 1 5.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL284861 IC50 = 2000.0 nM 5.70