Assay Detail
Binding
CHEMBL4041842
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Inhibition of GSK3beta (unknown origin)
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Natural and synthetic bioactive inhibitors of glycogen synthase kinase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 6.43 | 8.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL361708 | HYMENIALDISINE | — | 1 | 8.00 |
| CHEMBL352222 | — | — | 1 | 7.70 |
| CHEMBL102714 | SB-216763 | — | 1 | 7.47 |
| CHEMBL409450 | 6BIO | — | 1 | 5.82 |
| CHEMBL3545157 | TIDEGLUSIB | 2.0 | 1 | 5.70 |
| CHEMBL4073799 | — | — | 1 | 5.52 |
| CHEMBL1201279 | — | — | 1 | 4.82 |
| CHEMBL1234004 | LITHIUM ION | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL361708 | HYMENIALDISINE | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL352222 | — | IC50 | = | 20.0 | nM | 7.70 |
| CHEMBL102714 | SB-216763 | IC50 | = | 34.0 | nM | 7.47 |
| CHEMBL409450 | 6BIO | IC50 | = | 1500.0 | nM | 5.82 |
| CHEMBL3545157 | TIDEGLUSIB | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL4073799 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL1201279 | — | IC50 | = | 15000.0 | nM | 4.82 |
| CHEMBL1234004 | LITHIUM ION | IC50 | = | 2000000.0 | nM | - |