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Assay Detail

CHEMBL4041844

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of GST-tagged GSK3beta (unknown origin) expressed in Escherichia coli BL21-CodonPlus (DE3) by Z'-LYTE assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Glycogen synthase kinase-3 beta (CHEMBL262)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Natural and synthetic bioactive inhibitors of glycogen synthase kinase.
Khan I, Tantray MA, Alam MS, Hamid H.
Eur J Med Chem (2017) 125 : 464 -477
PubMed 27689729 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.47 6.47

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL564033 1 6.47

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL564033 IC50 = 340.0 nM 6.47