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Assay Detail

CHEMBL4041857

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of Staphylococcus aureus DNA gyrase using relaxed pBR322 DNA as substrate after 3 hrs by agarose electrophoresis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Staphylococcus aureus
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Linker-switch approach towards new ATP binding site inhibitors of DNA gyrase B.
Jukič M, Ilaš J, Brvar M, Kikelj D, Cesar J, Anderluh M.
Eur J Med Chem (2017) 125 : 500 -514
PubMed 27689732 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.00 8.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL36506 NOVOBIOCIN 4.0 1 8.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL36506 NOVOBIOCIN IC50 = 10.0 nM 8.00