Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL4042372

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to HCV genotype 2A JFH1 protease domain truncated NS3 helicase by fluorescence assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Hepatitis C virus JFH-1
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

In silico identification, design and synthesis of novel piperazine-based antiviral agents targeting the hepatitis C virus helicase.
Bassetto M, Leyssen P, Neyts J, Yerukhimovich MM, Frick DN, Courtney-Smith M, Brancale A.
Eur J Med Chem (2017) 125 : 1115 -1131
PubMed 27810598 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 6.24 6.24

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4066868 1 6.24

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4066868 Kd = 570.0 nM 6.24