Assay Detail
Binding
CHEMBL4042625
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of quorum sensing regulator protein pqsR in Pseudomonas aeruginosa PAO1 harboring reporter plasmid pqsA-gfp assessed as reduction in pqsA expression measured every 15 mins for 12 hrs by GFP-fluorescence assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Pseudomonas aeruginosa PAO1 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Disulfide Bond-Containing Ajoene Analogues As Novel Quorum Sensing Inhibitors of Pseudomonas aeruginosa.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.48 | 6.48 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4098007 | — | — | 1 | 6.48 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4098007 | — | IC50 | = | 330.0 | nM | 6.48 |