Assay Detail
Binding
CHEMBL4042771
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of PARP in Wistar rat pancreatic islet nuclear fraction using histone H1 as substrate in presence of [14C]NAD after 10 mins by scintillation counting method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Design, synthesis and biological activity of novel molecules designed to target PARP and DNA.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 5.30 | 5.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL81977 | 3-AMINOBENZAMIDE | — | 1 | 5.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL81977 | 3-AMINOBENZAMIDE | IC50 | = | 5000.0 | nM | 5.30 |