Assay Detail
Binding
CHEMBL4044716
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Competitive inhibition of almond beta-glucosidase pre-incubated for 1 hr followed by p-nitrophenyl-beta-D-glucopyranoside, substrate addition by fluorescence detection based assay
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Prunus dulcis |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
α-Geminal disubstituted pyrrolidine iminosugars and their C-4-fluoro analogues: Synthesis, glycosidase inhibition and molecular docking studies.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.74 | 6.74 |
| Ki | 1 | 6.84 | 6.84 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4059852 | — | — | 2 | 6.84 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4059852 | — | Ki | = | 144.0 | nM | 6.84 |
| CHEMBL4059852 | — | IC50 | = | 184.0 | nM | 6.74 |