Assay Detail
Functional
CHEMBL4046948
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against Coxsackievirus B3 Nancy infected in human Hep2 cells assessed as inhibition of virus-induced cytopathic effect after 48 hrs by neutral red uptake assay
13
Total Activities
13
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Coxsackievirus B3 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and anti-enterovirus activity of new analogues of MDL-860.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 13 | 5.09 | 5.57 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL343131 | — | — | 1 | 5.57 |
| CHEMBL4069452 | — | — | 1 | 5.24 |
| CHEMBL4101992 | — | — | 1 | 5.00 |
| CHEMBL4065053 | — | — | 1 | 4.53 |
| CHEMBL4090477 | — | — | 1 | - |
| CHEMBL4086499 | — | — | 1 | - |
| CHEMBL4102926 | — | — | 1 | - |
| CHEMBL4078652 | — | — | 1 | - |
| CHEMBL4084003 | — | — | 1 | - |
| CHEMBL4073636 | — | — | 1 | - |
| CHEMBL4094262 | — | — | 1 | - |
| CHEMBL4079598 | — | — | 1 | - |
| CHEMBL4097631 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL343131 | — | IC50 | = | 2700.0 | nM | 5.57 |
| CHEMBL4069452 | — | IC50 | = | 5800.0 | nM | 5.24 |
| CHEMBL4101992 | — | IC50 | = | 9900.0 | nM | 5.00 |
| CHEMBL4065053 | — | IC50 | = | 29600.0 | nM | 4.53 |
| CHEMBL4090477 | — | IC50 | - | — | - | |
| CHEMBL4086499 | — | IC50 | - | — | - | |
| CHEMBL4102926 | — | IC50 | - | — | - | |
| CHEMBL4078652 | — | IC50 | - | — | - | |
| CHEMBL4084003 | — | IC50 | - | — | - | |
| CHEMBL4073636 | — | IC50 | = | 426000.0 | nM | - |
| CHEMBL4094262 | — | IC50 | - | — | - | |
| CHEMBL4079598 | — | IC50 | - | — | - | |
| CHEMBL4097631 | — | IC50 | - | — | - |