Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL4047470

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Growth inhibition of human NALM16 cells after 72 hrs by CellTiter-Glo reagent based assay
16
Total Activities
16
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type NALM16
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Diverse amide analogs of sulindac for cancer treatment and prevention.
Mathew B, Hobrath JV, Connelly MC, Kiplin Guy R, Reynolds RC.
Bioorg Med Chem Lett (2017) 27 : 4614 -4621
PubMed 28935266 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 16 6.44 7.15

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4075613 1 7.15
CHEMBL4101979 1 7.01
CHEMBL4061941 1 6.52
CHEMBL4100716 1 6.46
CHEMBL4101299 1 6.31
CHEMBL4081616 1 5.89
CHEMBL4072732 1 5.72
CHEMBL2087735 1 -
CHEMBL4100190 1 -
CHEMBL4075863 1 -
CHEMBL4093457 1 -
CHEMBL4085818 1 -
CHEMBL4065134 1 -
CHEMBL4091765 1 -
CHEMBL4083989 1 -
CHEMBL4104867 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4075613 EC50 = 71.0 nM 7.15
CHEMBL4101979 EC50 = 97.0 nM 7.01
CHEMBL4061941 EC50 = 300.0 nM 6.52
CHEMBL4100716 EC50 = 350.0 nM 6.46
CHEMBL4101299 EC50 = 490.0 nM 6.31
CHEMBL4081616 EC50 = 1300.0 nM 5.89
CHEMBL4072732 EC50 = 1900.0 nM 5.72
CHEMBL2087735 EC50 - -
CHEMBL4100190 EC50 - -
CHEMBL4075863 EC50 - -
CHEMBL4093457 EC50 - -
CHEMBL4085818 EC50 - -
CHEMBL4065134 EC50 - -
CHEMBL4091765 EC50 - -
CHEMBL4083989 EC50 - -
CHEMBL4104867 EC50 - -