Assay Detail
Binding
CHEMBL4047726
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of porcine pancreatic lipase using p-nitrophenyl butyrate as substrate pretreated for 15 mins followed by substrate addition measured after 15 mins by spectrophotometric method
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Sus scrofa |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Plasma-induced dimerization of phloridzin as a new class of anti-adipogenic agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.18 | 6.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2354678 | — | — | 1 | 6.30 |
| CHEMBL4067236 | — | — | 1 | 5.28 |
| CHEMBL4094684 | — | — | 1 | 4.83 |
| CHEMBL45068 | PHLORETIN | — | 1 | 4.30 |
| CHEMBL4078162 | — | — | 1 | - |
| CHEMBL245067 | PHLORIZIN | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2354678 | — | IC50 | = | 500.0 | nM | 6.30 |
| CHEMBL4067236 | — | IC50 | = | 5200.0 | nM | 5.28 |
| CHEMBL4094684 | — | IC50 | = | 14700.0 | nM | 4.83 |
| CHEMBL45068 | PHLORETIN | IC50 | = | 50400.0 | nM | 4.30 |
| CHEMBL4078162 | — | IC50 | = | 257100.0 | nM | - |
| CHEMBL245067 | PHLORIZIN | IC50 | > | 300000.0 | nM | - |