Assay Detail
Binding
CHEMBL4047796
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]mesulergine from recombinant human 5-ht2C expressed in CHO cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Identification of selective 8-(piperidin-4-yloxy)quinoline sulfone and sulfonamide histamine H1 receptor antagonists for use in allergic rhinitis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 6.00 | 6.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL639 | AZELASTINE | 4.0 | 1 | 6.30 |
| CHEMBL4088036 | — | — | 1 | 5.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL639 | AZELASTINE | Ki | = | 501.19 | nM | 6.30 |
| CHEMBL4088036 | — | Ki | = | 1995.26 | nM | 5.70 |