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Assay Detail

CHEMBL4049558

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiparasitic activity against chloroquine-resistant Plasmodium falciparum
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Plasmodium falciparum
Confidence 1 — Organism
Curated By Autocuration

Target

Plasmodium falciparum (CHEMBL364)
Type ORGANISM
Organism Plasmodium falciparum

Publication

4-Hydroxyphenylpyruvate Dioxygenase and Its Inhibition in Plants and Animals: Small Molecules as Herbicides and Agents for the Treatment of Human Inherited Diseases.
Santucci A, Bernardini G, Braconi D, Petricci E, Manetti F.
J Med Chem (2017) 60 : 4101 -4125
PubMed 28128559 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.52 6.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4078793 1 6.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4078793 IC50 = 300.0 nM 6.52