Assay Detail
ADMET
CHEMBL4050868
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human MRC9 cells assessed as reduction in viability after 72 hrs by SRB assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | MRC9 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
6-OH-Phenanthroquinolizidine Alkaloid and Its Derivatives Exert Potent Anticancer Activity by Delaying S Phase Progression.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.62 | 8.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3356793 | — | — | 1 | 8.66 |
| CHEMBL4062427 | — | — | 1 | 8.57 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3356793 | — | IC50 | = | 2.2 | nM | 8.66 |
| CHEMBL4062427 | — | IC50 | = | 2.7 | nM | 8.57 |