Assay Detail
Functional
CHEMBL4050952
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Antiproliferative activity against human HL60/MX2 cells after 72 hrs by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HL60/MX2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
6-OH-Phenanthroquinolizidine Alkaloid and Its Derivatives Exert Potent Anticancer Activity by Delaying S Phase Progression.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.26 | 8.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3356793 | — | — | 1 | 8.77 |
| CHEMBL399454 | — | — | 1 | 6.55 |
| CHEMBL1417019 | MITOXANTRONE HYDROCHLORIDE | 4.0 | 1 | 6.46 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3356793 | — | IC50 | = | 1.7 | nM | 8.77 |
| CHEMBL399454 | — | IC50 | = | 278.3 | nM | 6.55 |
| CHEMBL1417019 | MITOXANTRONE HYDROCHLORIDE | IC50 | = | 350.7 | nM | 6.46 |