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Assay Detail

CHEMBL4052018

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against Influenza A virus (A2 Japan/305/57) H2N2 infected in MDCK cells assessed as reduction of virus-induced cytopathic effect after 4 to 5 days by MTS assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Influenza A virus (A/Japan/305/1957(H2N2))
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Slow but Steady Wins the Race: Dissimilarities among New Dual Inhibitors of the Wild-Type and the V27A Mutant M2 Channels of Influenza A Virus.
Barniol-Xicota M, Gazzarrini S, Torres E, Hu Y, Wang J, Naesens L, Moroni A, Vázquez S.
J Med Chem (2017) 60 : 3727 -3738
PubMed 28418242 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 5.48 5.48

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL294443 1 5.48

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL294443 EC50 = 3300.0 nM 5.48