Assay Detail
Functional
CHEMBL4052873
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Antiproliferative activity against human MDA-MB-231 cells after 72 hrs by MTS assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MDA-MB-231 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
A Versatile Method to Determine the Cellular Bioavailability of Small-Molecule Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.88 | 5.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4074243 | — | — | 1 | 5.64 |
| CHEMBL4065619 | — | — | 1 | 4.92 |
| CHEMBL3819506 | — | — | 1 | 4.62 |
| CHEMBL4086276 | — | — | 1 | 4.32 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4074243 | — | IC50 | = | 2300.0 | nM | 5.64 |
| CHEMBL4065619 | — | IC50 | = | 12000.0 | nM | 4.92 |
| CHEMBL3819506 | — | IC50 | = | 24000.0 | nM | 4.62 |
| CHEMBL4086276 | — | IC50 | = | 48000.0 | nM | 4.32 |