Assay Detail
Binding
CHEMBL4052985
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant KLK7 (unknown origin) expressed in zymogen form in Pichia pastorisstrain X-33 using KHLY-pNA as substrate after 30 mins
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Design of Potent and Selective Cathepsin G Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.73 | 7.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4061897 | — | — | 1 | 7.16 |
| CHEMBL4081142 | — | — | 1 | 6.89 |
| CHEMBL4092637 | — | — | 1 | 6.13 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4061897 | — | Ki | = | 69.0 | nM | 7.16 |
| CHEMBL4081142 | — | Ki | = | 130.0 | nM | 6.89 |
| CHEMBL4092637 | — | Ki | = | 740.0 | nM | 6.13 |