Assay Detail
Binding
CHEMBL4052986
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Inhibition of bovine chymotrypsin using Suc(OMe)-AAPV-MCA as substrate after 30 mins
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Bos taurus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Design of Potent and Selective Cathepsin G Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 4 | 7.68 | 8.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4061897 | — | — | 1 | 8.72 |
| CHEMBL4097952 | — | — | 1 | 7.46 |
| CHEMBL4081142 | — | — | 1 | 6.85 |
| CHEMBL4092637 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4061897 | — | Ki | = | 1.9 | nM | 8.72 |
| CHEMBL4097952 | — | Ki | = | 35.0 | nM | 7.46 |
| CHEMBL4081142 | — | Ki | = | 140.0 | nM | 6.85 |
| CHEMBL4092637 | — | Ki | > | 10000.0 | nM | - |