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Assay Detail

CHEMBL4052987

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of bovine trypsin using Boc-QAR-MCA as substrate after 30 mins
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Bos taurus
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Design of Potent and Selective Cathepsin G Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold.
Swedberg JE, Li CY, de Veer SJ, Wang CK, Craik DJ.
J Med Chem (2017) 60 : 658 -667
PubMed 28045523 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 6.24 6.24

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4092637 1 6.24

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4092637 Ki = 580.0 nM 6.24