Assay Detail
Binding
CHEMBL4052989
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human neutrophil elastase using Suc(OMe)-AAPV-pNA as substrate after 30 mins
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Design of Potent and Selective Cathepsin G Inhibitors Based on the Sunflower Trypsin Inhibitor-1 Scaffold.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 4.78 | 5.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4081142 | — | — | 1 | 5.05 |
| CHEMBL4061897 | — | — | 1 | 4.92 |
| CHEMBL4092637 | — | — | 1 | 4.37 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4081142 | — | Ki | = | 8900.0 | nM | 5.05 |
| CHEMBL4061897 | — | Ki | = | 12000.0 | nM | 4.92 |
| CHEMBL4092637 | — | Ki | = | 43000.0 | nM | 4.37 |