Assay Detail
Binding
CHEMBL4053421
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Inhibition of LPS-induced NF-kappaB (unknown origin) transactivation expressed in human SW480 cells administered 1 hr after LPS stimulation measured after 6 hrs by luciferase reporter gene assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Glycybridins A-K, Bioactive Phenolic Compounds from Glycyrrhiza glabra.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.13 | 5.26 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL561840 | — | — | 1 | 5.26 |
| CHEMBL229885 | LICOAGROCHALCONE A | — | 1 | 5.21 |
| CHEMBL233766 | — | — | 1 | 5.19 |
| CHEMBL139702 | LICOAGROCHACONE A | — | 1 | 4.86 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL561840 | — | IC50 | = | 5500.0 | nM | 5.26 |
| CHEMBL229885 | LICOAGROCHALCONE A | IC50 | = | 6200.0 | nM | 5.21 |
| CHEMBL233766 | — | IC50 | = | 6400.0 | nM | 5.19 |
| CHEMBL139702 | LICOAGROCHACONE A | IC50 | = | 13900.0 | nM | 4.86 |