Assay Detail
Functional
CHEMBL4053500
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Cytotoxicity against human A498 cells assessed as reduction in cell viability
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A498 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Englerins: A Comprehensive Review.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.94 | 7.35 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2024567 | ENGLERIN A | — | 1 | 7.35 |
| CHEMBL4101112 | — | — | 1 | 6.55 |
| CHEMBL4074369 | — | — | 1 | 6.02 |
| CHEMBL4098352 | — | — | 1 | 5.34 |
| CHEMBL4078718 | — | — | 1 | 4.46 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2024567 | ENGLERIN A | IC50 | = | 45.0 | nM | 7.35 |
| CHEMBL4101112 | — | IC50 | = | 280.0 | nM | 6.55 |
| CHEMBL4074369 | — | IC50 | = | 950.0 | nM | 6.02 |
| CHEMBL4098352 | — | IC50 | = | 4600.0 | nM | 5.34 |
| CHEMBL4078718 | — | IC50 | = | 35000.0 | nM | 4.46 |