Assay Detail
Binding
CHEMBL4053556
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human MetAP1
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
The Bengamides: A Mini-Review of Natural Sources, Analogues, Biological Properties, Biosynthetic Origins, and Future Prospects.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 6.25 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4079583 | — | — | 1 | 7.00 |
| CHEMBL327579 | — | — | 1 | 6.40 |
| CHEMBL256279 | BENGAMIDE A | — | 1 | 6.16 |
| CHEMBL4078211 | — | — | 1 | 6.16 |
| CHEMBL4061080 | — | — | 1 | 5.52 |
| CHEMBL4089242 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4079583 | — | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL327579 | — | IC50 | = | 400.0 | nM | 6.40 |
| CHEMBL256279 | BENGAMIDE A | IC50 | = | 700.0 | nM | 6.16 |
| CHEMBL4078211 | — | IC50 | = | 700.0 | nM | 6.16 |
| CHEMBL4061080 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL4089242 | — | IC50 | > | 10000.0 | nM | - |