Assay Detail
ADMET
CHEMBL4053586
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Antiproliferative activity against human IOSE-80 cells after 72 hrs by CellTiter 96 aqueous one solution assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | IOSE-80 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
(+)-Strebloside-Induced Cytotoxicity in Ovarian Cancer Cells Is Mediated through Cardiac Glycoside Signaling Networks.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.31 | 7.32 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL254219 | DIGITOXIN | 4.0 | 1 | 7.32 |
| CHEMBL449686 | STREBLOSIDE | — | 1 | 7.29 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL254219 | DIGITOXIN | IC50 | = | 48.4 | nM | 7.32 |
| CHEMBL449686 | STREBLOSIDE | IC50 | = | 50.9 | nM | 7.29 |