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Assay Detail

CHEMBL4056515

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antioxidant activity assessed as inhibition of ferrous sulfate-induced lipid peroxidation after 30 mins
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Publication

Phenylsulfonylfuroxan NO-donor phenols: Synthesis and multifunctional activities evaluation.
Xie Y, Yang Y, Li S, Xu Y, Lu W, Chen Z, Yang G, Li Y, Cao Y, Bian X.
Bioorg Med Chem (2017) 25 : 4407 -4413
PubMed 28651914 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 7 5.62 6.66

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4060853 1 6.66
CHEMBL4059922 1 6.44
CHEMBL4089052 1 6.15
CHEMBL2086817 1 5.29
CHEMBL196 ASCORBIC ACID 4.0 1 4.81
CHEMBL4074411 1 4.38
CHEMBL4093404 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4060853 IC50 = 221.0 nM 6.66
CHEMBL4059922 IC50 = 361.0 nM 6.44
CHEMBL4089052 IC50 = 713.0 nM 6.15
CHEMBL2086817 IC50 = 5132.0 nM 5.29
CHEMBL196 ASCORBIC ACID IC50 = 15350.0 nM 4.81
CHEMBL4074411 IC50 = 41421.0 nM 4.38
CHEMBL4093404 IC50 > 100000.0 nM -