Assay Detail
Functional
CHEMBL4056522
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Vasorelaxant activity against KCl Krebs solution-induced contraction in rat artery ring administered after KCl induction by myograph method
12
Total Activities
6
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Tissue | Artery |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Phenylsulfonylfuroxan NO-donor phenols: Synthesis and multifunctional activities evaluation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.97 | 6.38 |
| Activity | 6 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4059922 | — | — | 2 | 6.38 |
| CHEMBL4074411 | — | — | 2 | 6.17 |
| CHEMBL4093404 | — | — | 2 | 5.88 |
| CHEMBL2086817 | — | — | 2 | 5.87 |
| CHEMBL4089052 | — | — | 2 | 5.80 |
| CHEMBL4060853 | — | — | 2 | 5.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4059922 | — | IC50 | = | 414.0 | nM | 6.38 |
| CHEMBL4074411 | — | IC50 | = | 674.53 | nM | 6.17 |
| CHEMBL4093404 | — | IC50 | = | 1333.52 | nM | 5.88 |
| CHEMBL2086817 | — | IC50 | = | 1342.76 | nM | 5.87 |
| CHEMBL4089052 | — | IC50 | = | 1599.56 | nM | 5.80 |
| CHEMBL4060853 | — | IC50 | = | 2004.47 | nM | 5.70 |
| CHEMBL4093404 | — | Activity | - | — | - | |
| CHEMBL4074411 | — | Activity | - | — | - | |
| CHEMBL2086817 | — | Activity | - | — | - | |
| CHEMBL4060853 | — | Activity | - | — | - | |
| CHEMBL4089052 | — | Activity | - | — | - | |
| CHEMBL4059922 | — | Activity | - | — | - |