Assay Detail
Binding
CHEMBL4056546
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human CDK4/CyclinD3 by enzymatic radiometric assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Discovery of a highly potent, selective and novel CDK9 inhibitor as an anticancer drug candidate.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.37 | 7.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3545110 | RIBOCICLIB | 4.0 | 1 | 7.89 |
| CHEMBL4078060 | — | — | 1 | 6.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3545110 | RIBOCICLIB | IC50 | = | 13.0 | nM | 7.89 |
| CHEMBL4078060 | — | IC50 | = | 142.0 | nM | 6.85 |