Assay Detail
Functional
CHEMBL4058027
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Cytotoxicity against human U251MG cells assessed as reduction in cell viability after 72 hrs by CyQuant dye-based assay
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | U-251 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Bioactive polyprenylated benzophenone derivatives from the fruits extracts of Garcinia xanthochymus.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 5.56 | 5.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4082502 | — | — | 1 | 5.89 |
| CHEMBL4100517 | — | — | 1 | 5.75 |
| CHEMBL510949 | XANTHOCHYMOL | — | 1 | 5.64 |
| CHEMBL458934 | CAMBOGIN | — | 1 | 5.55 |
| CHEMBL4077067 | — | — | 1 | 5.46 |
| CHEMBL4062269 | — | — | 1 | 5.43 |
| CHEMBL1098255 | ISOXANTHOCHYMOL | — | 1 | 5.22 |
| CHEMBL4059505 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4082502 | — | IC50 | = | 1300.0 | nM | 5.89 |
| CHEMBL4100517 | — | IC50 | = | 1800.0 | nM | 5.75 |
| CHEMBL510949 | XANTHOCHYMOL | IC50 | = | 2300.0 | nM | 5.64 |
| CHEMBL458934 | CAMBOGIN | IC50 | = | 2800.0 | nM | 5.55 |
| CHEMBL4077067 | — | IC50 | = | 3500.0 | nM | 5.46 |
| CHEMBL4062269 | — | IC50 | = | 3700.0 | nM | 5.43 |
| CHEMBL1098255 | ISOXANTHOCHYMOL | IC50 | = | 6000.0 | nM | 5.22 |
| CHEMBL4059505 | — | IC50 | - | — | - |