Assay Detail
Binding
CHEMBL4058235
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at DOR in CD-1 mouse vasa deferentia assessed as inhibition of electrically induced contractions after 5 mins
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Development of novel LP1-based analogues with enhanced delta opioid receptor profile.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 7.25 | 8.36 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4102093 | — | — | 1 | 8.36 |
| CHEMBL4066846 | — | — | 1 | 7.97 |
| CHEMBL4079574 | — | — | 1 | 7.93 |
| CHEMBL4077833 | — | — | 1 | 6.10 |
| CHEMBL3759092 | — | — | 1 | 5.91 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4102093 | — | IC50 | = | 4.4 | nM | 8.36 |
| CHEMBL4066846 | — | IC50 | = | 10.8 | nM | 7.97 |
| CHEMBL4079574 | — | IC50 | = | 11.8 | nM | 7.93 |
| CHEMBL4077833 | — | IC50 | = | 793.5 | nM | 6.10 |
| CHEMBL3759092 | — | IC50 | = | 1240.0 | nM | 5.91 |