Assay Detail
Functional
CHEMBL4058978
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Inhibition of metabolic activity in human PANC1 cells after 72 hrs by resazurin assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | PANC-1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
RNA G-Quadruplexes in Kirsten Ras (KRAS) Oncogene as Targets for Small Molecules Inhibiting Translation.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.32 | 6.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3745930 | — | — | 1 | 6.58 |
| CHEMBL469320 | — | — | 1 | 6.05 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3745930 | — | IC50 | = | 260.0 | nM | 6.58 |
| CHEMBL469320 | — | IC50 | = | 900.0 | nM | 6.05 |