Assay Detail
Binding
CHEMBL4119174
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Inhibition of ascorbic acid/methylene blue activated recombinant human IDO expressed in Escherichia coli using L-Tryptophan as substrate after 60 mins by spectrophotometric method
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Polyketides and Anthranilic Acid Possessing 6-Deoxy-α-l-talopyranose from a Streptomyces Species.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.35 | 6.43 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL590 | MENADIONE | 4.0 | 1 | 6.43 |
| CHEMBL2172467 | NAPHTHOMYCIN A | — | 1 | 6.36 |
| CHEMBL4126044 | — | — | 1 | 6.25 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL590 | MENADIONE | IC50 | = | 370.0 | nM | 6.43 |
| CHEMBL2172467 | NAPHTHOMYCIN A | IC50 | = | 440.0 | nM | 6.36 |
| CHEMBL4126044 | — | IC50 | = | 560.0 | nM | 6.25 |