Assay Detail
Functional
CHEMBL4119178
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Antiproliferative activity against human SW480 cells after 48 hrs by MTT assay
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | SW480 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Polyketides and Anthranilic Acid Possessing 6-Deoxy-α-l-talopyranose from a Streptomyces Species.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 4.77 | 6.39 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 6.39 |
| CHEMBL2172467 | NAPHTHOMYCIN A | — | 1 | 5.12 |
| CHEMBL4126044 | — | — | 1 | 5.03 |
| CHEMBL4128526 | — | — | 1 | 4.64 |
| CHEMBL4129893 | — | — | 1 | 4.11 |
| CHEMBL272733 | PIERICIDIN A | — | 1 | 4.09 |
| CHEMBL4127284 | — | — | 1 | 4.03 |
| CHEMBL4128668 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 406.0 | nM | 6.39 |
| CHEMBL2172467 | NAPHTHOMYCIN A | IC50 | = | 7600.0 | nM | 5.12 |
| CHEMBL4126044 | — | IC50 | = | 9300.0 | nM | 5.03 |
| CHEMBL4128526 | — | IC50 | = | 23000.0 | nM | 4.64 |
| CHEMBL4129893 | — | IC50 | = | 78100.0 | nM | 4.11 |
| CHEMBL272733 | PIERICIDIN A | IC50 | = | 82100.0 | nM | 4.09 |
| CHEMBL4127284 | — | IC50 | = | 94300.0 | nM | 4.03 |
| CHEMBL4128668 | — | IC50 | > | 100000.0 | nM | - |