Assay Detail
Binding
CHEMBL4121192
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Inhibition of GST-tagged ULK1 (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Serine/threonine-protein kinase ULK1 (CHEMBL6006) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
UNC-51-like Kinase 1: From an Autophagic Initiator to Multifunctional Drug Target.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.62 | 8.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3605057 | — | — | 1 | 8.54 |
| CHEMBL4127042 | — | — | 1 | 7.35 |
| CHEMBL4128069 | — | — | 1 | 6.97 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3605057 | — | IC50 | = | 2.9 | nM | 8.54 |
| CHEMBL4127042 | — | IC50 | = | 45.0 | nM | 7.35 |
| CHEMBL4128069 | — | IC50 | = | 108.0 | nM | 6.97 |