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Assay Detail

CHEMBL4121856

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ADMET
Cytotoxicity in human L-132 cells assessed as reduction in cell viability incubated for 48 hrs by MTT assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type ADMET
Organism Homo sapiens
Cell Type L132
Confidence 1 — Organism
Curated By Intermediate

Target

L132 (CHEMBL613999)
Type CELL-LINE
Organism Homo sapiens

Publication

Synthesis of 1,2,4-triazole-linked urea/thiourea conjugates as cytotoxic and apoptosis inducing agents.
Tokala R, Bale S, Janrao IP, Vennela A, Kumar NP, Senwar KR, Godugu C, Shankaraiah N.
Bioorg Med Chem Lett (2018) 28 : 1919 -1924
PubMed 29657100 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.82 4.82

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4129059 1 4.82

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4129059 IC50 = 15180.0 nM 4.82