Assay Detail
Functional
CHEMBL4123798
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human PC3/DTX cells after 3 days by WST-1 assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Optimized synthesis and antiproliferative activity of desTHPdactylolides.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.21 | 5.63 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL92 | DOCETAXEL ANHYDROUS | 4.0 | 1 | 5.63 |
| CHEMBL4129744 | — | — | 1 | 5.42 |
| CHEMBL4128735 | — | — | 1 | 5.36 |
| CHEMBL4128045 | — | — | 1 | 4.84 |
| CHEMBL4129818 | — | — | 1 | 4.81 |
| CHEMBL4126462 | — | — | 1 | - |
| CHEMBL4129422 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL92 | DOCETAXEL ANHYDROUS | IC50 | = | 2340.0 | nM | 5.63 |
| CHEMBL4129744 | — | IC50 | = | 3770.0 | nM | 5.42 |
| CHEMBL4128735 | — | IC50 | = | 4410.0 | nM | 5.36 |
| CHEMBL4128045 | — | IC50 | = | 14400.0 | nM | 4.84 |
| CHEMBL4129818 | — | IC50 | = | 15420.0 | nM | 4.81 |
| CHEMBL4126462 | — | IC50 | > | 30000.0 | nM | - |
| CHEMBL4129422 | — | IC50 | > | 20000.0 | nM | - |