Assay Detail
Functional
CHEMBL4123804
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Antiproliferative activity against human PC3 cells after 72 hrs by methylene blue staining based assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | PC-3 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Optimized synthesis and antiproliferative activity of desTHPdactylolides.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.68 | 6.12 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4129061 | — | — | 1 | 6.12 |
| CHEMBL4128045 | — | — | 1 | 5.52 |
| CHEMBL4129818 | — | — | 1 | 5.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4129061 | — | IC50 | = | 750.0 | nM | 6.12 |
| CHEMBL4128045 | — | IC50 | = | 3050.0 | nM | 5.52 |
| CHEMBL4129818 | — | IC50 | = | 4020.0 | nM | 5.40 |