Assay Detail
Binding
CHEMBL4124010
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of CYP19 (unknown origin) by Becton Dickinson aromatase assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Design and synthesis of functionalized piperazin-1yl-(E)-stilbenes as inhibitors of 17α-hydroxylase-C17,20-lyase (Cyp17).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.45 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4128368 | — | — | 1 | 6.00 |
| CHEMBL157101 | KETOCONAZOLE | 4.0 | 1 | 5.80 |
| CHEMBL4129721 | — | — | 1 | 5.00 |
| CHEMBL4126284 | — | — | 1 | 5.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4128368 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL157101 | KETOCONAZOLE | IC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL4129721 | — | IC50 | = | 10000.0 | nM | 5.00 |
| CHEMBL4126284 | — | IC50 | = | 10000.0 | nM | 5.00 |