Assay Detail
Binding
CHEMBL4124571
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human LDH5 using pyruvate as substrate after 10 mins
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Computer-aided discovery and biological characterization of human lactate dehydrogenase 5 inhibitors with anti-osteosarcoma activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 6.91 | 8.14 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4065858 | — | — | 1 | 8.14 |
| CHEMBL4126746 | — | — | 1 | 6.41 |
| CHEMBL4126939 | — | — | 1 | 6.17 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4065858 | — | EC50 | = | 7.2 | nM | 8.14 |
| CHEMBL4126746 | — | EC50 | = | 390.0 | nM | 6.41 |
| CHEMBL4126939 | — | EC50 | = | 670.0 | nM | 6.17 |